Having won the last World Cup tournament held in Brazil in 1950, Uruguay would love to complete a unique double by reaching the Final and succeeding once again.
Despite being grouped with fellow former winners Italy and England, they are expected to qualify from the group. With an easier Second Round game to look forward to, Uruguay will look to reach the quarter-finals and take it from there.
HOW URUGUAY GOT TO THE 2014 WORLD CUP
Uruguay were the last of the 32 sides to confirm their place at the 2014 World Cup.
Finishing fifth in the CONMEBOL qualification table on goal difference, Uruguay had to enter a Playoff against AFC side Jordan.
Uruguay made their superiority count in the Playoff, running out 5-0 winners in last November's first leg. A 0-0 draw in Uruguay then assured the South Americans of the final spot in Brazil.
URUGUAY MANAGER AND TRACK RECORD
Oscar Tabarez will lead Uruguay into a second successive World Cup - after being in charge for their Fourth-placed finish four years ago, before winning Uruguay's fourth Copa America title in 2011.
Uruguay's World Cup triumph in Brazil in 1950 was the second time they lifted the Jules Rimet trophy, having also won on home soil in the inaugural tournament held in 1930.
URUGUAY KEY PLAYER
After being the top CONMEBOL Qualifying scorer with 11 goals - with four coming in the 4-0 home win over Chile - Luis Suarez ensured he retained his status as Uruguay's prime target man.
Uruguay's all-time top scorer with 39 goals in 71 appearances, the 27-year-old has also been almost unstoppable for Liverpool this season - after taking just 15 games to break the record of fewest games to reach 20 Premier League goals.
Currently in the form of his life, Suarez is sure to be one of the stars of the 2014 World Cup - as long as he can avoid some of the controversial actions that have repeatedly dogged his career so far.
URUGUAY 2014 WORLD CUP BETTING TIP
Uruguay will be better equipped to deal with the conditions in Brazil than England and Italy, so expect them to qualify out of the group ahead of one of the European sides.
With Group C not providing much in the way of Second Round opponents, Uruguay will surely have enough about them to reach the quarter-finals of the 2014 World Cup (at least.)
URUGUAY 2014 WORLD CUP SQUAD
Goalkeepers: Fernando Muslera, Martin Silva, Rodrigo Munoz.
Defenders: Maximiliano Pereira, Diego Lugano, Diego Godin, Jose Maria Gimenez, Sebastian Coates, Martin Caceres, Jorge Fucile.
Midfielders: Alejandro Silva, Alvaro Gonzalez, Alvaro Pereira, Walter Gargano, Egidio Arevalo Rios, Diego Perez, Sebastian Eguren, Cristian Rodriguez, Gaston Ramirez, Nicolas Lodeiro.
Forwards: Luis Suarez, Edinson Cavani, Abel Hernandez, Diego Forlan, Christian Stuani.