Arsenal make the trip north to Hull, as the Gunners seek to reaffirm their Premier League title credentials.
After a 5-0 hammering of FC Porto in the Champions League on Tuesday, Arsene Wenger's side will look to continue their free-scoring form in pursuit of their first league championship win since 2004's 'Invincibles'.
Arsenal however will again be without captain fantastic Cesc Fabregas, with the Spaniard's hamstring injury meaning he'll stay on the sidelines.
Former Barcelona man Fabregas is his team's highest goalscorer this campaign, but Danish international Nicklas Bendtner sprang to life in the midweek rout.
After being castigated for missing a hatful of chances last weekend against Burnley at the Emirates, he managed a hat-trick to book Arsenal's place in the quarter finals of Europe's premier club competition.
Bendtner's odds have dramatically shortened as a result and he is 9/2 with Extrabet to be first goalscorer in the 5.30pm kick-off.
With Bendtner confidently claiming earlier in the season that he will be the top goal-getter in the Premier League one day, Wenger is backing his young striker to go on improving.
"It shows you how football can change very quickly," said Wenger.
"He came back with good focus and the same belief, that is one of his strengths as well.
"Nicklas had not lost the confidence, it remains relatively stable."
Hull City go into the game desperate for points but also anxious to forget a training ground bust-up between Nicky Barmby and Jimmy Bullard earlier in the week, which was unfortunately seen by members of the local Women's Institute.
Manager Phil Brown has since apologised to those who witnessed the brawl and played down the incident.