Brazilian midfield ace, Elano may be out for the remainder of World Cup 2010 after limping out of Tuesday’s training session.
He misses tomorrow’s game against Holland along with the suspended Ramires who collected a second yellow card against Chile.
Depite the weakened Brazilian midfield, bookmakers are only prepared to offer odds on for Brazil to win in normal time.
Betting odds of even money are available on betting exchanges and Betfair are offering up to £25 free bet when new customers sign up.
Elano, 29, picked up an ankle injury in a challenge by Côte d'Ivoire defender Cheik Tiote in Brazil's 3-1 win which ensured progress into the second stage of the tournament.
He missed the final group game against Portugal and the 3-0 victory over Chile in the round of sixteen.
Hopeful of recovery in time to play in the crucial fixture against a strong Netherlands outfit, he unfortunately limped out of Tuesday’s training with fears his World Cup could be over.
Brazil's team doctor Jose Luiz Runco told reporters: "I'm not saying that he won't be able to play again at this World Cup but he won't be ready for Friday.
"He has bad bruising and it was after he trained on Sunday that he said that he was having problems.
"The bone is swollen and we have to release the pressure on it so he will do nothing strenuous for the rest of the week."
"We still hope he can play next week but I can't say that he will be able to categorically."