The weekend spotlight shone on the Manning brothers when the two quarterbacks squared up in Indianapolis for the second time in an action packed second week in the NFL.
Online bookmakers are offering free bets to new customers that can be redeemed on American Football games this season.
Four-time MVP Peyton Manning threw for three touchdowns in the Colt’s easy 38-14 win against his younger brother’s New York Giants.
Eli came off second best as he was forced into two fumbles to hand Indianapolis 14 points.
In New York, second-year quarterback Mark Sanchez silenced his critics by outperforming Tom Brady leading the Jets to a 28-14 win over the Patriots.
Sanchez completed 21-of-30 passes for 220 yards and three touchdowns while Brady was 20-of-36 for 248 yards and two touchdowns but was intercepted twice.
The Minnesota Vikings were left to rue the handling of quarterback Brett Favre who fumbled the ball inside his own end zone in a 14-10 loss to the Miami Dolphins.
Linebacker Koa Misi recovered Favre's fumble in the end zone to score with six minutes left in the third quarter and give Miami a 14-0 lead.
The Vikings reached the NFC title decider last year under Favre's direction but are already playing catch-up after NFC North rivals the Green Bay Packers and Chicago Bears have both won the first two games.
Super Bowl favourites, Green Bay Packers thrashed the Buffalo Bills 34-7, without the help of tailback Ryan Grant and defensive end Justin Harrell, who were injured against Philadelphia last week.
Aaron Rodgers passed for two touchdowns and rushed for another and finished with 255 yards through the air.
Boylesports are offering odds of 7/1 for the Packers to go on to win Super Bowl XLV in February 2011.
The Bears chalked up their second win of the season with a 27-20 win over the Dallas in Texas to leave the Cowboys winless after two games.
Jay Cutler threw for 277 yards and three touchdowns for the Bears while Dallas quarterback Tony Romo completed 35 of 51 passes for 374 yards and a touchdown but threw two first-half interceptions.
Michael Vick completed 21 of 34 passes for 284 yards and two touchdowns to lead the visiting Philadelphia Eagles to a 35-32 victory over the Detroit Lions.
The Pittsburgh Steelers recovered from losing starting quarterback Dennis Dixon to a knee injury in the second quarter to beat the Tennessee Titans 19-11.
Ryan Succop booted his third field goal of the game with 7:41 left as the Kansas City Chiefs held on for a 16-14 victory over the Cleveland Browns.
The Tampa Bay Buccaneers took advantage of turnovers to beat the Carolina Panthers 20-7.
Mike Nugent kicked five field goals and the Cincinnati Bengals intercepted Joe Flacco four times in a 15-10 win over Baltimore.
Jason Snelling scored three touchdowns as the Atlanta Falcons thrashed the Arizona Cardinals 41-7 at the Georgia Dome.
The San Diego Chargers got back on track after their season-opening defeat six days ago, when Philip Rivers led the defending AFC West champions to a 38-13 win over the Jacksonville Jaguars.
Rivers completed 22 of 29 passes for 334 yards and three touchdowns while the Chargers delivered a rock-solid defensive display to give their home fans plenty to celebrate on a sunny afternoon at Qualcomm Stadium.
Matt Schaub threw for three touchdowns and a whopping 497 yards as the Houston Texans beat the Washington Redskins 30-27 in overtime on a 35-yard field goal by Neil Rackers.
WEEK TWO RESULTS;
SUNDAY 19 SEPTEMBER:
Arizona 7-41 Atlanta
Tampa Bay 20-7 Carolina
Baltimore 10-15 Cincinnati
Kansas City 16-14 Cleveland
Chicago 27-20 Dallas
Philadelphia 35-32 Detroit
Buffalo 7-34 Green Bay
Miami 14-10 Minnesota
Pittsburgh 19-11 Tennessee
Seattle 14-31 Denver
St. Louis 14-16 Oakland
New England 14-28 N.Y. Jets
Jacksonville 13-38 San Diego
Houston 30-27 Washington
N.Y. Giants 14-38 Indianapolis
MONDAY 20 SEPTEMBER
New Orleans at San Francisco