Eagles host the Colts with the big story around this game being that Eagles quarterback Michael Vick is set to start after missing the last two games with injury.
Their opponents the Colts, led by the talismanic Peyton Manning at quarterback are looking to win their third straight away game to fire them to sole posession of the AFC South lead.
The Colts had a good win against the Houston Texans last time out despite having injuries to key weapons on offense in Austin Collie, running back Joseph Addai and Mannings big target at tight end Dallas Clark.
Manning again proved that he could lead the Colts to victory. The injury situation has not improved this week for the colts either; can they defy the odds against a strong Eagles outfit?
Bookies think not by making the Eagles 3 point favourites in this game which is probably fair when you look at the matchup.
Though the Eagles have struggled against the Colts in recent years this must be a great chance to turn them over.
The Colts have the 28th ranked run defence which bodes well for the eagles' running back Colt McCoy who will look to post some big numbers and open up the passing game for QB Michael Vick who lets not forget doesn't mind a run himself!
Vick has not thrown an interception in 96 passes so far which leads the league and will be hopefull that star receiver DeSean Jackson will be back after missing the Eagles' last game.
The Eagles also come off a bye week which has given them extra time to work on their game plan and rectify mistakes they made when giving up 27 fourth quarter points in their latest loss to Tennessee Titans.
Take the Eagles to clinch a much needed home victory in this one with Extrabet who offer the Eagles -3 points at EVENS.