Leeds Rhinos v Castleford Tigers
The West Yorkshire rivals meet in front of the live BBC cameras on Saturday tea-time with Leeds desperate for a win in their first game since Richard Agar stepped down.
Castleford will fancy their chances of an upset and this is a tough one to call.
With the prices on offer, back an upset with a Tigers victory available at a hugely tempting 15/8 with Unibet.
Tip: Jake Mamo anytime try-scorer at 21/10 with Bet 365.
Warrington Wolves v Wakefield Trinity
Daryl Powell is under huge pressure to stop the rot at Warrington after three straight Super League defeats.
Wakefield won at the Halliwell Jones Stadium and Powell knows that another defeat in the Challenge Cup would leave him under pressure.
But Trinity have proved they can win at Warrington, so back them to do so again at 49/20 with 888 Sport.
Tip: Wakefield to win +10 on the handicap at 10/11 with Bet 365.